Logo USU 1

THE DOCTORAL PROGRAM

IN PHARMACEUTICAL SCIENCES

USU FACULTY OF PHARMACY

TTU Logo
MASTER

The curriculum for the Doctoral Program (S-3) in Pharmacy is a regular track with a maximum of 50 credits, which are arranged in groups of compulsory subjects, electives, proposal writing, qualification exams, research, and dissertation exams. For the research path, the credit load is 44 credits. The following is a list of courses and their descriptions:

LIST OF COURSES OF DOCTORAL PROGRAMME IN PHARMACEUTICAL SCIENCES (REGULAR COURSE)

FACULTY OF PHARMACY UNIVERSITAS SUMATERA UTARA

No. Course Code Course Credit Semester
1 DIF1831 Clinical Pharmacy 3 I
2 DIF1851 Science Philosophy 2
3 DIF1853 Research Methodology 2
4 DIF1821 Pharmaceutical Technology 3
5 DIF2823 Biopharmaceutics* 3 II
6 DIF2813 Structure Elucidation* 3
7 DIF2824 Pharmaceutics* 3
8 DIF2834 Clinical Pharmacology I (Antimicrobial and Anticancer)* 3
9 DIF2835 Clinical Pharmacology II (Cardiovascular)* 3
10 DIF2836 Clinical Pharmacology III (Endocrine) * 3
11 DIF2832 Drug Information* 3
12 DIF2812 Instrument II (Pharmacology) * 3
13 DIF2811 Instrument I (Pharmaceutical Chemistry) * 3
14 DIF2831 Medication Error* 3
15 DIF2841 Good Pharmaceutical Practice* 3
16 DIF2821 Drug Delivery I (Oral) * 3
17 DIF2822 Drug Delivery II (Topical) * 3
18 DIF2814 Technology of Food Chemistry* 3
19 DIF2833 Clinical Toxicology* 3
20 DIF3841 Journal Appreciation 1 III
21 DIF3843 Research I 5
22 DIF3842 Seminar of Research Proposal (Colloquium) 1
23 DIF4841 Appreciation of Research Result I 1 IV
24 DIF4843 Research II 5
25 DIF4842 Research Seminar I 1
26 DIF5841 Appreciation of Research Result II 1 V
27 DIF5843 Research III 5
28 DIF5842 Research Seminar II 1
29 DIF6841 Dissertation Seminar 1 VI
30 DIF6842 Dissertation Examination 9
Credit Total 50

Note:

*Maximum elective course in Semester II is 9 SKS                                                                      


COURSE DESCRIPTION OF DOCTORAL PROGRAMME IN PHARMACEUTICAL SCIENCES

(REGULARFACULTY OF PHARMACYUNIVERSITAS SUMATERA UTARA

Semester I
Course Name Pharmaceutical Technology
Course Code DIF1821
Course Description
  1. Technology to deliver drugs to cancer cells
  2. Nanoparticle manufacturing technology
  3. Technology to provide drug release based on physiological or therapeutic needs.

Semester I
Course Name Clinical Pharmacy
Course Code DIF1831
Course Description
  1. Introduction to Clinical Pharmacy and Therapy
  2. Adverse Drug Reaction (ROM)
  3. DRP related to drug interactions (IO)
  4. Clinical Pharmacy and Therapeutic Schizophrenia
  5. Drug Therapy Remated Problem (DRP)
  6. Therapeutic Drug Monitoring (TDM)
  7. Pharmacoeconomics
  8. Clinical Pharmacy and Hypertension therapy
  9. Clinical Pharmacy and therapy for Cardiac Heart Failure (CHF)
  10. Medication Error (ME)
  11. Evidence Based Medicine (EBM)
  12. Clinical Pharmacy and Ulcer Therapy
  13. Clinical Pharmacy and Asthma Therapy
  14. Clinical Pharmacy and Diabetes Mellitus (DM) Therapy

Semester I
Course Name Philosophy of Science
Course Code DIF 1851
Course Description
  1. Basic Concepts and Introduction to Philosophy (1 and 2)
  2. Basic Concepts and Introduction to Philosophy of Science (1 and 2)
  3. Dimensions and scope of the study of philosophy of science (1 and 2)
  4. Science Problems (1 and 2)
  5. Development and application of theory
  6. History of the Development of Science
  7. Principles of Methodology
  8. Substance of Philosophy of Science
  9. Reasoning in the context of philosophy
  10. The role of science in the development of civilization and culture
  11. Scientific Ethics and Science Development Strategies

Semester I
Course Name Research Methodology
Course Code DIF 1853
Course Description
  1. Types of Knowledge and Theory of Truth
  2. Ways of acquiring knowledge
  3. Scientific Method and scientific way of thinking
  4. Classification of Research Methods and their application
  5. Understanding the Research Problem and how to find it.
  6. Applying Scientific Thinking in Writing Proposals
  7. Problem Formulation and Hypotheses
  8. Research variables
  9. Trial Design
  10. Sampling method
  11. Instrumentation in Research
  12. Observation and Data Collection
  13. Statistics and its application in research
  14. Data processing and presentation
  15. Evaluation of the Dissertation Proposal
  16. Writing research reports and dissertations
  17. Writing Articles for publication

Semester II
Course Name Instrumentation I (Chemistry)
Course Code DIF 2811
Course Description
  1. MS, IR and UV instruments
  2. 1H-NMR and 13C-NMR instruments
  3. Application of instruments in the elucidation of structures
  4. Inductively coupled plasma atomic emission
  5. Mass Spectrometry
  6. Mass Spectrometry of Volatile Analytes (Journal I)
  7. Simultaneous LC/MS/MS Determine Compound in Eine (Journal 2)
  8. Solid Phase Extrusion
  9. GC & HPLC
  10. IR Spectrometer
  11. NMR Spectrometer

Semester II
Course Name Instrumentation II (Pharmacology)
Course Code DIF 2812
Course Description
  1. Introduction to pharmacological test analysis instrumentation and its use
  2. Understand the working principle of the tool
  3. Using tools (instrumentation)
  4. Identify test result data
  5. Interpret and analyze test result data

Semester II
Course Name Structure Elucidation
Course Code DIF 2813
Course Description
  1. MS, IR and UV data interpretation application
  2. Application of 1H-NMR and 13C-NMR data interpretation
  3. Application of isolated compounds
  4. Application to synthesized compounds

Semester II
Course Name Food Chemistry Technology
Course Code DIF 2814
Course Description
  1. The chemistry of water and its function as a nutrient
  2. Chemistry of Carbohydrates
  3. Properties and classification of carbohydrates
  4. Carbohydrate Modification
  5. Lipid
  6. Chemical Fat
  7. Fatty Acid
  8. Factors affecting the chemical, physical and biochemical properties of fats
  9. Quality and nutritional value of Food fat
  10. Modified Pagan Fats
  11. Atherogenicity of Dietary Fats
  12. Fat Substitutes and Fat Replacers
  13. Amino Acids, Peptides and Proteins
  14. Physical, Chemical and Biochemical Properties of Food Proteins
  15. Quality and Nutritional Value of Food Protein
  16. Food Protein Modification
  17. ​​Food Processing
  18. Food Preservation
  19. Food Canning
  20. Fermented Food
  21. Food Additives
  22. Food Damage and Pollution
  23. Food Safety and Toxicology
  24. Food preservation
  25. Food preservation (continued)
  26. Food chemistry technology in meat and its products
  27. Food chemistry technology in meat and its products (continued)
  28. Fermented food
  29. Food chemistry technology in milk and its products

Semester II
Course Name Drug Delivery I (Oral)
Course Code DIF 2821
Course Description
  1. Gastric targeted drug delivery
  2. Small intestine targeted drug delivery
  3. Colon targeted drug delivery

Semester II
Course Name Drug Delivery (Topical)
Course Code DIF 2822
Course Description
  1. Dermatological formulation
  2. Wound healing

Semester II
Course Name Biopharmaceutics
Course Code DIF 2823
Course Description
  1. INTRODUCTION
    1. Particle Size,
    2. Solubility (Passive Diffusion and Partition Coefficient )
    3. Ionization (Hendersen-Hasselbalch Equation)
    4. Surface Area
    5. Effect of Temperature, Hydrolysis and Oxidation on Drug Absorption
    6. DRUG DELIVERY ROUTES

Discussing the Intravascular and Extravascular Administration

  1. PHYSIOLOGICAL AND BIOLOGICAL FACTORS AFFECTING DRUG ABSORPTION
  2. Discuss the physiological and biological factors of the body on drug absorption
  3. DISPOSITION
    1. Drug Elimination
    2. Drug Absorption
    3. Residual Method
    4. The Wagner Nelson Method
    5. BIODIVENESS AVAILABILITY

Discussing about ABSOLUTE and RELATIVE Bioavailability

Semester II
Course Name Pharmaceutics
Course Code DIF 2824
Course Description
  1. Introduction to Pharmacokinetics
  2. Mathematical Models in Pharmacokinetics
  3. Open Compartment Model and Non-Compartment Model
  4. Residual Model
  5. Absorption Pharmacokinetics
  6. Distribution Pharmacokinetics
  7. Elimination Pharmacokinetics
  8. Multiple Dosing and Dosing Regimen
  9. Non-linear Pharmacokinetics
  10. Physiological factors on drug absorption
  11. Physiological factors on drug distribution and protein binding
  12. Hepatic and Renal Elimination of Drugs
  13. Pharmacogenetics
  14. The role of Pharmacokinetics in clinical conditions

Semester II
Course Name Medication Error
Course Code DIF 2831
Course Description
  1. Roots of Bottling Errors (Identify events and actions that lead to Medication Errors)
  2. Prevention of Medication Errors (Identify strategies to appropriately prevent risks of nursing practice that cause ME)
  3. Strategies to know ME that might happen by coworkers
  4. System Failures and Root Cause Analysis (Examines the adverse effects of ME on patients, facilities, and health care systems and determines the role of system failures in ME management)
  5. My Personal Improvement Plan (Initiate a personal improvement plan to prevent medication errors)
  6. ME Prevention related to Prescribing
  7. Prevention of errors in dispensing and effective use of dispensing automation
  8. ME is related to drug administration and The role of pharmaceutical trademarks in ME
  9. High Alert Medication and the role of drug packaging & labeling in ME
  10. The role of patients in ME . prevention
  11. ME prevention in cancer chemotherapy
  12. ME prevention in pediatrics
  13. The role of risk management in ME prevention
  14. Risk Analysis and ME Treatment

Semester II
Course Name Drug Information
Course Code DIF 2832
Course Description
  1. Introduction to the Concept of Medicine Information
  2. Modification of a systematic approach to answering questions
  3. Formulation of Effective Responses and Recommendations: A structured approach
  4. Drug Information Source
  5. Electronic drug Information Management
  6. Evaluation of Literature I: Clinical Trial Control
  7. Evaluation of Literature II: Beyond Basic
  8. Pharmacoeconomics (FE) at a glance
  9. Evidence-Based Clinical Practice Guidelines
  10. Application of Statistical Analysis in Clinic
  11. Writing Professionally
  12. Legal Responsibilities for Provision of Drug Information
  13. Ethical Aspects of Drug Information Practice
  14. Pharmacy and Therapeutic Committee

Semester II
Course Name Clinical Technology
Course Code DIF 2833
Course Description
  1. Diagnosis and Treatment of Poisoning.
  2. The process of detoxifying toxic compounds that enter the body
  3. Food poisoning and pollution
  4. Heavy Metal Poisoning

Semester II
Course Name Clinical Pharmacology I (Antimicrobial & Anticancer)
Course Code DIF 2834
Course Description
  1. Overview of Microorganism Biology
  2. Infection I and Chemotherapy
  3. Infection II-Antibacterial
  4. Infection III-Bacterial Chemotherapy
  5. Bacterial Resistance to Antibiotics
  6. Factors influencing the selection of antimicrobial agents
  7. An overview of the natural history and epidemiology of cancer
  8. Viruses -Tumors and Cellular Oncogenes
  9. Growth factor and cytoplasmic receptor signaling circuit
  10. Tumor suppressor pRb gene and cell cycle clock
  11. p53 and Apoptosis Immortalization
  12. Tumor immunology, detection and diagnostics
  13. Tumor Microenvironment, Heterotypic Interactions and Angiogenesis; Invasion and Metastasis
  14. Therapy: Chemotherapy, Radiation, Immunotherapy, and Complementary Medicine

Semester II
Course Name Clinical Pharmacology II (Cardiovascular)
Course Code
Course Description
  1. Introduction to the Cardiovascular System
  2. Blood and Veins
  3. The heart and considerations of anatomy, physiology, and conduction system
  4. Cardiovascular Disease (Coronary Artery Disease, Inflammation, C-Reactive Protein as a Biomarker; Vulnerability and Plaques)
  5. Cardiovascular Disease (Heart Hypertrophy)
  6. Pathophysiology and Clinical Impact of Diastolic Heart Failure
  7. Myocarditis and its Management
  8. Atherosclerosis associated with plaque: Pathophysiology, detection, Treatment
  9. Coronary Heart Disease: Regulation of Coronary Blood Flow; Stable angina treatment
  10. Treatment of Unstable Angina, Acute Non–ST-Elevation Myocardial Infarction
  11. Coronary Artery Spasm Pattern and Treatment
  12. Pattern of acute STEMI (Acute ST-Elevation Myocardial Infarction) and Treatment
  13. Vascular Remodeling in Healthy Hearts and Vascular Endothelium Cell Function Problems and Thrombosis
  14. The potential of stem cell regeneration in the treatment of heart disease

Semester II
Course Name Clinical Pharmacology III (Endocrine)
Course Code DIF 2836
Course Description
  1. Overview of the Endocrine System
  2. Overview of the endocrine in the head
  3. Overview of endocrine in the neck region
  4. Adrenal endocrine review
  5. An endocrine review of the female genitalia
  6. Endocrine review of the male genitalia
  7. Endocrinology I (Adrenal cortex, Corticotrophin, Corticosteroids and antagonists)
  8. Endocrinology II (Diabetes mellitus, Insulin, and Oral hypoglycemics)
  9. Endocrinology III (Thyroid hormones, Thyroid disorders, and Antithyroid drugs)
  10. Endocrinology IV (Hypothermic and pituitary hormones, Hypothalamic pituitary disorders)
  11. Endocrinology V (Sex hormones, Contraception, Uterus, and Reproductive disorders)
  12. An evidence-based approach to endocrine problems (osteoporosis)
  13. An evidence-based approach to endocrine problems (Pituitary tumors)
  14. An evidence-based approach to endocrine problems (Menopause, and reproductive dysfunction)

Semester II
Course Name Good Pharmacy Practice
Course Code DIF 2841
Course Description
  1. Pharmacy Practice
  2. Good Pharmacy Practice
  3. The role of pharmacists
  4. Pharmaceutical Care (Pharmaceutical Care)
  5. Competencies of Pharmacists (Professional Competencies for Pharmacist)
  6. Continuing Professional Development
  7. Good Distribution Practices
  8. Related Laws and Regulations: Law No.36/2009 on Health; Law No.36/2014 concerning Health Workers; PP. No. 51/2009 concerning Pharmaceutical Work; PMK No. 72/73/74 concerning Pharmaceutical Service Standards

Semester III
Course Name Journal Appreciation
Course Code DIF 3841
Course Description
  1. Search for written journals that are relevant to the student's field or dissertation plan
  2. Preparation of materials to be presented in front of the relevant lecturer
  3. Preparation by students of related materials from the journals they are looking for
  4. Submission and discussion by the student concerned about

Semester III
Course Name Seminar of Research Proposal (Colloquium)
Course Code DIF 3842
Course Description
  1. Research proposals
  2. Submission of research proposals
  3. Discussion/input related to research proposals
  4. Evaluation of research proposals by the supervisory committee and examiners

Semester III
Course Name Research I
Course Code DIF 3843
Course Description
  1. Conducting experiments and/or research as part of the entire research
  2. Compile and make a report on the results of research I

Semester IV
Course Name Appreciation of Research Result I
Course Code DIF 4841
Course Description
  1. Assessment of research results I by the supervisory commission
  2. Discuss the results of research I by students with the supervisory commission

Semester IV
Course Name Seminar of Research Result I
Course Code DIF 4842
Course Description
  1. Research result report I has been approved by the supervisory commission
  2. Submission/presentation of research results I in front of a commission of examiners who have been appointed by the study program
  3. Questions and answers and/or discussion of research results I by the supervisory commission and examiners
  4. Assessment by the supervisory committee and examiners

Semester IV
Course Name Research II
Course Code DIF 4843
Course Description
  1. Continuing research I
  2. Compile and make reports on research results II

Semester V
Course Name Appreciation of Research Result II
Course Code DIF 5841
Course Description
  1. Discuss the results of research II with the supervisory commission
  2. Assessment of the results of research II by the supervisory commission

Semester V
Course Name Seminar Hasil Penelitian II
Course Code DIF 5842
Course Description
  1. Research report II that has been approved by the supervisory commission
  2. Submission/presentation of research results I in front of the examining committee and the supervisory commission
  3. Questions and answers and/or discussion of research results I by the supervisory commission and examiners
  4. Assessment by the supervisory committee and examiners

Semester V
Course Name Research III
Course Code DIF 5843
Course Description
  1. Continuing research II
  2. Compile and make reports on research results III

Semester VI
Course Name Seminar of Dissertation Result
Course Code DIF 6841
Course Description
  1. Report on research results from research I, II and III
  2. Submission of summaries of research results I, II and III in front of the supervisory commission and examiners
  3. Discussion of the results of research I, II and III by the supervisory commission and examiners
  4. Assessment by the supervisory committee and examiners

Semester VI
Course Name Dissertation Examination
Course Code DIF 6842
Course Description

Closed-Examination

  1. Submission of the dissertation in front of the supervisory committee and examiners in a closed manner
  2. Questions and answers/discussions/dissertation discussions by the supervisory committee and examiners
  3. Assessment by the supervisory committee and examiners
  4. Determination of graduation by the supervisory committee and examiners

OPENED-EXAMINATION/DOCTORAL PROMOTION

  1. Presentation of the results of the dissertation research in front of the chairman of the session, the supervisory commission and examiners
  2. Questions and answers by the chairman of the session, the supervisory committee and examiners
  3. Graduation determination meeting by the chairman of the session, the supervisory commission and examiners
  4. Announcement of the results of the meeting to determine the graduation of the dissertation exam by the chairman of the session, the supervisory commission and examiners

Super User